GH 0,3 Retinol-NP Bi-gel Serum: the global anti-ageing treatment that works on every sign of ageing at once

Pure retinol is the most scientifically validated anti-ageing active in dermatological science, and GH 0,3 Retinol-NP by Gema Herrerías is its most complete expression: 0.3% anhydrous retinol in its purest form, stabilised in omega 3, 6 and 9-rich soybean oil to maximise penetration and tolerance, synergised with 4% niacinamide — which amplifies efficacy and improves tolerance — and hexapeptide-10 Serilesine®, one of the most documented firming peptides on the market. The bi-gel texture — a combination of aqueous and oil phase in one bottle — allows rapid, sensorial absorption with no residue. The result is a total anti-ageing treatment that simultaneously addresses wrinkles, sagging, dark spots, uneven texture and pores.

Action and Benefits

• Global anti-wrinkle action: reduces expression lines and deep wrinkles by stimulating synthesis of collagen, elastin and hyaluronic acid.
• Firming: hexapeptide-10 Serilesine® reinforces the dermo-epidermal junction, increasing firmness and elasticity (+27%).
• Depigmenting: niacinamide prevents melanosome transfer, reducing dark spots and uneven tone.
• Regulates sebum and improves pore appearance in oily or acne-prone skin.
• Antioxidant and antiglycation properties: protects collagen from oxidative damage and glycation.
• Stimulates cell renewal and gently exfoliates, improving texture and luminosity.
• Non-comedogenic. Clinically proven. Night-time use. Not suitable during pregnancy or breastfeeding.

Key Active Ingredients

• 0.3% Anhydrous Pure Retinol (stabilised in omega 3, 6 and 9 soybean oil): purest form of retinol, with greater efficacy than hydrated versions. Stabilisation in unsaturated fatty acid-rich soybean oil protects its activity and improves skin tolerance. Stimulates collagen, elastin and HA synthesis, accelerates cell turnover, reduces wrinkles, regulates sebum and has depigmenting properties.
• 4% Niacinamide (Vitamin B3): anti-inflammatory, reduces redness and improves retinol tolerance. Antioxidant, anti-ageing and depigmenting. Prevents dark spot formation by acting on melanin transfer to keratinocytes.
• 1% Hexapeptide-10 (Serilesine®): biomimetic peptide synthesised from a laminin adhesion sequence. Acts with dual cellular activity on keratinocytes and fibroblasts, favouring synthesis of laminin-5, α6-integrin and hemidesmosomes. Reinforces the dermo-epidermal junction. Provides +95% protection against HA and collagen degradation. Improves elasticity by up to +27%.
• White Flower Extract (Jasmine, Rosa Centifolia, Bellis Perennis): antiglycation and antioxidant complex that protects collagen from glycation damage, one of the less-known causes of skin ageing.
• Chamomile Extract (Chamomilla Recutita): soothing and anti-inflammatory, improves retinol tolerance.
• Grapefruit Extract (Citrus Grandis Fruit Extract): antioxidant and astringent, adds luminosity and reinforces depigmenting action.

How to Apply

• Apply 4 or 5 drops to clean, dry skin at night in a thin layer.
• Progressive use according to tolerance: for skin not accustomed to retinol, start 3 nights per week and increase gradually.
• Avoid application to the neck, eye contour, lip corners and nose wings to prevent irritation.
• For dry skin, apply GH Función Barrera Piel Seca 15 minutes later.
• Broad-spectrum sunscreen use during the day is mandatory.
• Not suitable during pregnancy or breastfeeding. Store between 10 and 30°C. PAO: see packaging.